and relatives, memantine can be said to be usually well tolerated, and to offer modest benefits for patients with moderate – severe dementia. Common side effects of Namenda include fatigue, pain, increased blood pressure, dizziness, headache, constipation, vomiting, back pain, confusion, sleepiness, hallucinations, coughing, and difficulty breathing. May 24, 2017 1 0. Memantine may cause side effects in some people, but they may vary from person to person. Description: Memantine, a derivative of amantadine, is a noncompetitive N-methyl-D-aspartate (NMDA)-receptor antagonist which binds preferentially to NMDA-receptor-operated cation channels.It blocks the action of glutamate, the principal excitatory neurotransmitter in the CNS. Memantine is the only FDA-approved drug for the treatment of Alzheimer's disease that is not an acetyl cholinesterase inhibitor. Side effects are generally minor and do not require medical attention in most cases. To reduce the risk of adverse effects memantine should be started at a low dose and slowly increased over a month. Memantine. Below is a summary of known side effects for Memantine. Because these side effects are so uncommon, it is difficult to tell whether they are actually caused by memantine or something else. Memantine Side–Effects Given that memantine has met FDA approval for medical use, the majority of scientific evidence supports the overall safety and effectiveness of memantine. Before using Memantine Hydrochloride, inform your doctor about your current list of medications, over the counter products (e.g. Memantine's side effects include fatigue, increases in blood pressure, dizziness, headache, constipation, confusion, and sleepiness, among others. If you notice any other effects, check with your healthcare professional. pregnancy, upcoming surgery, etc. Side Effects. Ivory Registered User. Email. Reddit. Most of the dose is excreted unchanged in the urine, so a lower dose is needed if renal function is reduced. Memantine is usually well tolerated. License: Except as otherwise noted, this work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.For commercial use or customized versions, please contact biobyte solutions GmbH.. Disclaimer: The content of this database of side effects (adverse drug reactions) is intended for educational and scientific research purposes only. However, there are some memantine side effects that are potentially serious and that should be reported to your healthcare provider, including hallucinations, an allergic reaction, and painful or difficulty breathing. So Ive been on memantine 5mg/day for 3 days now, feeling a little bit spaced out so to speak. In rats, foetal growth reduction was noted at exposure levels, which are identical or slightly higher than at human exposure. Namenda (memantine) is a prescription Alzheimer's medication used to treat dementia associated with Alzheimer's disease and improve memory and attention. Memantine: Formulations, Dosages, Contraindications, and Side Effects. Memantine side effects, will they fade? Side effects can be less likely for people who start treatment by taking the lower prescribed dose for at least a month (see ‘Taking the drugs’). Buy Memantine Online. Contents of the pack and other information 1. Call your doctor for medical advice about side effects. Memantine Hydrochloride - Side Effects. Adverse Reactions Most common adverse reactions (≥ 5 % and greater than placebo) are dizziness, headache, confusion and constipation. There is some clinical evidence that it can help people recover from stimulant and opioid addictions. The side effects usually get better after 2 weeks of taking the medication. First day I was fine, but the second day and also today I noticed a fair bit of ear,neck and back of the head pressure/pains, and some minor back soreness. Call your doctor if you have any unusual problems while taking this medication. You may report side effects to the FDA at 1-800-FDA-1088. It is used to treat moderate to severe dementia of the Alzheimer’s type. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) … Rare side effects of memantine occurred in less than 2 percent of people taking the drug. headache dizziness sleepiness tiredness high blood pressure problems with balance feeling sick difficulty sleeping confusion hallucinations It belongs to a group of It can cause dizziness, headaches, tiredness, elevated BP and constipation (common side effects – around 1-10 in 100). Pin. Body aches, dizziness, constipation, and headache may occur. Background: Cognitive dysfunction is very common in multiple sclerosis (MS) and it severely impairs patients' quality of life. If you notice any other effects, check with your healthcare professional. Share; Tweet What other drugs will affect memantine (Namenda, Namenda XR)? Research suggests that Namenda has a small effect in reducing symptoms among those diagnosed with moderate or severe cases of Alzheimer’s. Memantine can cause side effects that may impair your thinking or reactions. Share. This medicine is not an AChE inhibitor. . It is less preferred than acetylcholinesterase inhibitors such as donepezil. It is taken by mouth. M.A. Alone, the drug is safe when used properly; however, Memantine HCL use can be deadly when combined with drugs in … Precautions; Portions of this document last updated: Oct. 01, 2020. Multiple trials have found that memantine can attenuate some of the side-effects of cocaine abuse. Other side effects not listed may also occur in some patients. ), allergies, pre-existing diseases, and current health conditions (e.g. Memantine HCl Side Effects With so many benefits for mood and memory disorders, the nootropic community tends to assume that this drug comes with high risk of side effects. How to store Memantine hydrochloride 6. Side effects, drug interactions, dosing, and pregnancy and breastfeeding information is provided. Namenda (Memantine) Side Effects & Adverse Reactions. Act Memantine: Memantine belongs to the group of medications known as NMDA receptor antagonists. Keiski, in New Therapeutics for Traumatic Brain Injury, 2017. Find everything you need to know about Namenda (Memantine), including what it is used for, warnings, reviews, side effects, and interactions. Call your doctor for medical advice about side effects. Thread starter Ivory; Start date May 24, 2017; I. What Memantine hydrochloride is and what it is used for Memantine hydrochloride contains the active substance memantine hydrochloride. Memantine HCL is not known to cause addiction but, used in high dosages and in conjunction with other substances, can lead to dangerous side effects. Other side effects not listed may also occur in some patients. ).Some health conditions may make you more susceptible to the side-effects of the drug. vitamins, herbal supplements, etc. pregnancy, upcoming surgery, etc. Thus, we explored whether memantine might improve cognitive performance in patients with MS. Methods: We conducted a pilot trial with memantine (30 mg/day) in patients with MS with cognitive impairment. You may report side effects to the FDA at 1-800-FDA-1088. Some side effects can be serious. 21 Shares. It works by blocking the effects of an excessive amount of a chemical in the brain called glutamate. Consumer information about the medication memantine (Namenda), a drug used for the treatment of moderate to severe dementia of the Alzheimer's type. ), allergies, pre-existing diseases, and current health conditions (e.g. Treatment should only be continued if beneficial effects are seen. There is a good chance that these "side effects" could be completely unrelated to memantine. If, however, there is more confusion, sleepiness and general confusion, this drug may not be worth the cost or the other complications. Memantine may be useful for treating substance abuse and dependence. Please share your own experience with Namenda and Namenda side effects below in the comment section. Many side effects wear off over time. ).Some health conditions may make you more susceptible to the side-effects of the drug. Memantine: Uses & Side Effects. Memantine does not cure Alzheimer's disease, but it is used to decrease the symptoms. Common side effects … Possible side effects 5. Before using Memantine Hcl, inform your doctor about your current list of medications, over the counter products (e.g. It is a derivative of amantadine and is pharmacologically related to compounds like PCP, ketamine, and DXM, although its recreational use is comparatively rare. Memantine is used for moderate or severe Alzheimer's disease. Memantine reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer’s disease. The drug is completely absorbed even if taken with food. Be careful if you drive or do anything that requires you to be awake and alert. The side effects of memantine are less common and less severe than for the cholinesterase inhibitors. Some people do seem to benefit from Namenda (Memantine). Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. Memantine hydrochloride has been marketed as Namenda by Forest Laboratories in the United States and as Ebixa by Lundbeck in Europe, although generic formulations of the tablets are now available. It is generally well-tolerated, and does not appear to cause an unusually high rate of negative side-effects [ 36 ]. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.. vitamins, herbal supplements, etc. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately: shortness of breath ; hallucination (seeing things or hearing voices that do not exist) Memantine may cause other side effects. Namenda (Memantine) is a drug that was approved by the FDA in 2003 for the treatment of Alzheimer’s disease. Tell your doctor about all your current medicines … Memantine was not teratogenic in rats and rabbits, even at maternally toxic doses, and no adverse effects of memantine were noted on fertility. 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